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- 910个与DNA损伤和修复紧密相关的化合物集合，是高通量筛选，高内涵筛选的良好载体；
- 涵盖与DNA损伤和修复相关的热门靶点，如HDAC、DNA/RNA Synthesis、Topoisomerase等；
- 通过临床前研究和临床实验，生物活性和生物安全性得到保障；
- 结构多样，药效显著，可渗透细胞；
- 详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
- NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。
DNA 损伤和修复分子库
DNA Damage & Repair Compound Library
癌细胞的耐药性是癌症治疗过程中面临的主要挑战，因此鉴定新的生物学靶标，并开发设计相应的药物成为重要策略，在各种潜在候选靶标中，癌细胞 DNA Damage & Repair 系统是重要的靶标。由于抗生素的滥用，细菌等微生物的耐药性越来越强，开发靶向微生物 DNA Damage & Repair 系统的药物迫在眉睫。 TargetMol DNA 损伤和修复分子库是910 个与DNA 损伤和修复紧密相关的化合物集合，可用于DNA 损伤和修复相关研究的高通量筛选，高内涵筛选。
TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。
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化合物库相关信息
Excel
SDF
联系我们获取更多批次信息产品编号 L3900
DNA 损伤和修复分子库规格
- 1 mg
- 30 μL x 10 mM (in DMSO)
- 50 μL x 10 mM (in DMSO)
- 100 μL x 10 mM (in DMSO)
- 250 μL x 10 mM (in DMSO)
询价 & 定制
产品描述
包装和储存
- 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
- 干粉蓝冰运输，DMSO溶液干冰运输；
- 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。
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化合物库组成
DNA/RNA Synthesis
DNA/RNA Synthesis
DNA/RNA Synthesis
Apoptosis
Apoptosis
Apoptosis
PPAR
PPAR
PPAR
HDAC
HDAC
HDAC
Autophagy
Autophagy
Autophagy
Topoisomerase
Topoisomerase
Topoisomerase
PARP
PARP
PARP
Antibacterial
Antibacterial
Antibacterial
Antibiotic
Nucleoside Antimetabolite/Analog
Nucleoside Antimetabolite/Analog
Antibiotic
Antibiotic
Nucleoside Antimetabolite/Analog
Sirtuin
Sirtuin
Sirtuin
Endogenous Metabolite
Endogenous Metabolite
Endogenous Metabolite
DNA-PK
DNA-PK
DNA-PK
DUB
DUB
DUB
PI3K
PI3K
PI3K
ATM/ATR
ATM/ATR
ATM/ATR
DNA Alkylator/Crosslinker
DNA Alkylator/Crosslinker
DNA Alkylator/Crosslinker
ADC Cytotoxin
ADC Cytotoxin
ADC Cytotoxin
Influenza Virus
Influenza Virus
Influenza Virus
mTOR
mTOR
mTOR
HIV Protease
NF-κB
Parasite
HIV Protease
NF-κB
Parasite
HIV Protease
NF-κB
Parasite
DNA Alkylation
DNA Alkylation
DNA Alkylation
DHFR
HSV
DNA
DHFR
HSV
DNA
DHFR
HSV
DNA
Dehydrogenase
Caspase
COX
Dehydrogenase
COX
Caspase
Dehydrogenase
Caspase
COX
Telomerase
Telomerase
Telomerase
DNA gyrase
DNA gyrase
DNA gyrase
Mitophagy
Reactive Oxygen Species
Mitophagy
Reactive Oxygen Species
Mitophagy
Reactive Oxygen Species
BCL
Antifolate
SARS-CoV
Wnt/beta-catenin
Antifolate
BCL
SARS-CoV
Wnt/beta-catenin
Antifolate
BCL
SARS-CoV
Wnt/beta-catenin
Virus Protease
Antifungal
Virus Protease
Antifungal
Virus Protease
Antifungal
p53
p38 MAPK
Potassium Channel
p53
p38 MAPK
Potassium Channel
p53
p38 MAPK
Potassium Channel
AMPK
Ferroptosis
PDE
AMPK
PDE
Ferroptosis
AMPK
Ferroptosis
PDE
CRISPR/Cas9
Lipoxygenase
P450
Tyrosinase
HCV Protease
Antifection
Akt
CDK
HBV
Lipoxygenase
P450
CRISPR/Cas9
Antifection
HCV Protease
Akt
CDK
Tyrosinase
HBV
Lipoxygenase
P450
CRISPR/Cas9
Tyrosinase
Antifection
HCV Protease
Akt
CDK
HBV
Epigenetic Reader Domain
PKC
AChR
GABA Receptor
TNF
BMI-1
MTH1
Reverse Transcriptase
AChR
Epigenetic Reader Domain
PKC
TNF
GABA Receptor
BMI-1
MTH1
Reverse Transcriptase
AChR
Epigenetic Reader Domain
PKC
GABA Receptor
TNF
BMI-1
MTH1
Reverse Transcriptase
PKA
Drug Metabolite
Prostaglandin Receptor
TGF-beta/Smad
IL Receptor
STAT
Bcr-Abl
DNA Methyltransferase
Nrf2
Drug Metabolite
PKA
IL Receptor
STAT
Prostaglandin Receptor
TGF-beta/Smad
Bcr-Abl
DNA Methyltransferase
Nrf2
Drug Metabolite
PKA
IL Receptor
STAT
Prostaglandin Receptor
TGF-beta/Smad
Bcr-Abl
DNA Methyltransferase
Nrf2
ABC
Adenosine Receptor
Calcium Channel
MMP
Cannabinoid Receptor
Sodium Channel
transporter
Carbonic Anhydrase
FLT
P-gp
TRP/TRPV Channel
EGFR
LDL
MMP
ABC
Adenosine Receptor
Calcium Channel
Cannabinoid Receptor
Sodium Channel
Carbonic Anhydrase
FLT
P-gp
TRP/TRPV Channel
transporter
EGFR
LDL
MMP
ABC
Adenosine Receptor
Calcium Channel
Cannabinoid Receptor
Sodium Channel
transporter
Carbonic Anhydrase
FLT
P-gp
TRP/TRPV Channel
EGFR
LDL
Carboxypeptidase
Cysteine Protease
Immunology/Inflammation related
Anti-infection
Antiviral
GPR
Tyrosine Kinases
RAAS
Thrombin
Transferase
ERK
HIF/HIF Prolyl-Hydroxylase
IAP
PAK
Phospholipase
VEGFR
ATPase
Casein Kinase
Gamma-secretase
IκB/IKK
Mdm2
Microtubule Associated
Mitochondrial Metabolism
NO Synthase
PAFR
Retinoid Receptor
Syk
Arginase
Free radical scavengers
Interleukin
JAK
Adrenergic Receptor
cGAS
c-Met/HGFR
JNK
MEK
PI4K
Proteasome
Anti-infection
Antiviral
GPR
Tyrosine Kinases
Carboxypeptidase
Cysteine Protease
Immunology/Inflammation related
ATPase
Casein Kinase
Gamma-secretase
IκB/IKK
Mdm2
Microtubule Associated
Mitochondrial Metabolism
NO Synthase
PAFR
Retinoid Receptor
Syk
ERK
HIF/HIF Prolyl-Hydroxylase
IAP
PAK
Phospholipase
VEGFR
Arginase
Free radical scavengers
Interleukin
JAK
RAAS
Thrombin
Transferase
Adrenergic Receptor
cGAS
c-Met/HGFR
JNK
MEK
PI4K
Proteasome
Anti-infection
Antiviral
GPR
Tyrosine Kinases
Carboxypeptidase
Cysteine Protease
Immunology/Inflammation related
RAAS
Thrombin
Transferase
ATPase
Casein Kinase
Gamma-secretase
IκB/IKK
Mdm2
Microtubule Associated
Mitochondrial Metabolism
NO Synthase
PAFR
Retinoid Receptor
Syk
ERK
HIF/HIF Prolyl-Hydroxylase
IAP
PAK
Phospholipase
VEGFR
Arginase
Free radical scavengers
Interleukin
JAK
Adrenergic Receptor
cGAS
c-Met/HGFR
JNK
MEK
PI4K
Proteasome
5-HT Receptor
Aminopeptidase
Antioxidant
Aromatase
Dopamine Receptor
NOD-like Receptor (NLR)
PLK
Aurora Kinase
c-Kit
Fatty Acid Synthase
Histamine Receptor
PDGFR
Trk receptor
Androgen Receptor
c-Myc
FLAP
Glucokinase
LRRK2
MAO
NADPH
CCR
Epoxide Hydrolase
KLF
MLK
P2Y Receptor
Phosphatase
Proton pump
ROS
SGK
E1/E2/E3 Enzyme
Histone Demethylase
IDO
IGF-1R
Integrin
P2X Receptor
ROCK
RSV
Serine/threonin kinase
c-RET
Glutathione Peroxidase
HER
Histone Acetyltransferase
Leukotriene Receptor
Monoamine Oxidase
PAD
TAM Receptor
c-Fms
FAK
Hedgehog/Smoothened
HSP
MAPK
NMDAR
NOD
OCT
ribosome
Src
TLR
Aurora Kinase
c-Kit
Fatty Acid Synthase
Histamine Receptor
PDGFR
Trk receptor
5-HT Receptor
Aminopeptidase
Antioxidant
Aromatase
Dopamine Receptor
NOD-like Receptor (NLR)
PLK
E1/E2/E3 Enzyme
Histone Demethylase
IDO
IGF-1R
Integrin
P2X Receptor
ROCK
RSV
Serine/threonin kinase
CCR
Epoxide Hydrolase
KLF
MLK
P2Y Receptor
Phosphatase
Proton pump
ROS
SGK
c-RET
Glutathione Peroxidase
HER
Histone Acetyltransferase
Leukotriene Receptor
Monoamine Oxidase
PAD
TAM Receptor
Androgen Receptor
c-Myc
FLAP
Glucokinase
LRRK2
MAO
NADPH
c-Fms
FAK
Hedgehog/Smoothened
HSP
MAPK
NMDAR
NOD
OCT
ribosome
Src
TLR
Aurora Kinase
c-Kit
Fatty Acid Synthase
Histamine Receptor
PDGFR
Trk receptor
5-HT Receptor
Aminopeptidase
Antioxidant
Aromatase
Dopamine Receptor
NOD-like Receptor (NLR)
PLK
Androgen Receptor
c-Myc
FLAP
Glucokinase
LRRK2
MAO
NADPH
E1/E2/E3 Enzyme
Histone Demethylase
IDO
IGF-1R
Integrin
P2X Receptor
ROCK
RSV
Serine/threonin kinase
CCR
Epoxide Hydrolase
KLF
MLK
P2Y Receptor
Phosphatase
Proton pump
ROS
SGK
c-RET
Glutathione Peroxidase
HER
Histone Acetyltransferase
Leukotriene Receptor
Monoamine Oxidase
PAD
TAM Receptor
c-Fms
FAK
Hedgehog/Smoothened
HSP
MAPK
NMDAR
NOD
OCT
ribosome
Src
TLR
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