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Anti-CCL2 Monoclonal Antibody-APC
产品编号 TMAZ-0376A
别名 Monocyte secretory protein JE, Monocyte chemotactic protein 1, Monocyte chemotactic and activating factor, HC11, Small-inducible cytokine A2, C-C motif chemokine 2, Monocyte chemoattractant protein 1
Anti-CCL2 Monoclonal Antibody-APC is a biotin-conjugated rabbit antibody targeting CCL2. Anti-CCL2 Monoclonal Antibody-APC can be used in ELISA, FACS.
Anti-CCL2 Monoclonal Antibody-APC
Anti-CCL2 Monoclonal Antibody-APC
产品编号 TMAZ-0376A 别名 Monocyte secretory protein JE, Monocyte chemotactic protein 1, Monocyte chemotactic and activating factor, HC11, Small-inducible cytokine A2, C-C motif chemokine 2, Monocyte chemoattractant protein 1
Anti-CCL2 Monoclonal Antibody-APC is a biotin-conjugated rabbit antibody targeting CCL2. Anti-CCL2 Monoclonal Antibody-APC can be used in ELISA, FACS.
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产品介绍
生物活性
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抗原信息
化学信息
| 产品描述 | Anti-CCL2 Monoclonal Antibody-APC is a biotin-conjugated rabbit antibody targeting CCL2. Anti-CCL2 Monoclonal Antibody-APC can be used in ELISA, FACS. |
| 别名 | Monocyte secretory protein JE, Monocyte chemotactic protein 1, Monocyte chemotactic and activating factor, HC11, Small-inducible cytokine A2, C-C motif chemokine 2, Monocyte chemoattractant protein 1 |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of CCL2 overexpressed 446F cells with TMAZ-0376A, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| 应用 | ELISA, FACS |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Single-pass type I membrane |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of CCL2 protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 研究背景 | Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:10529171, PubMed:10587439, PubMed:9837883). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed:10587439, PubMed:9837883). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (PubMed:8195247, PubMed:8627182, PubMed:9792674). May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis (PubMed:8107690) |
| 其他可选修饰符 | Biotin/PE/AF488/AF555/AF647 |
| 可提供抗体种类 | 1 |
| 免疫原 | CCL2 |
| 抗原种属 | Human |
| 基因ID | 6347 |
| Uniprot ID | |
| 研究领域 | Cancer Research |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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