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Anti-ICAM1 Monoclonal Antibody-AF488
产品编号 TMAZ-0131A4
别名 Intercellular adhesion molecule 1, Major group rhinovirus receptor
Anti-ICAM1 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting ICAM1. Anti-ICAM1 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
Anti-ICAM1 Monoclonal Antibody-AF488
Anti-ICAM1 Monoclonal Antibody-AF488
产品编号 TMAZ-0131A4 别名 Intercellular adhesion molecule 1, Major group rhinovirus receptor
Anti-ICAM1 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting ICAM1. Anti-ICAM1 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μg | 询价 | 7日内发货 | |
| 100 μg | 询价 | 7日内发货 |
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产品介绍
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偶联与修饰
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| 产品描述 | Anti-ICAM1 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting ICAM1. Anti-ICAM1 Monoclonal Antibody-AF488 can be used in ELISA, FACS. |
| 别名 | Intercellular adhesion molecule 1, Major group rhinovirus receptor |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of ICAM1 overexpressed 293F cells with TMAZ-0131A4BI, which was counjucated with SA-PE (red). The WT 293F control is black line. |
| 应用 | ELISA, FACS |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of ICAM1 protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 研究背景 | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation|(Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins|(Microbial infection) Acts as a receptor for Coxsackievirus A21 capsid proteins|(Microbial infection) Upon Kaposi's sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell |
| 偶联 | AF488 |
| 其他可选修饰符 | Biotin/APC/PE/AF555/AF647 |
| 可提供抗体种类 | 2 |
| 免疫原 | ICAM1 |
| 抗原种属 | Human |
| 基因ID | 3383 |
| Uniprot ID | |
| 研究领域 | Cancer Research |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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