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Anti-IL1R1 Monoclonal Antibody-APC
产品编号 TMAZ-0067A
别名 Interleukin-1 receptor alpha, Interleukin-1 receptor type I, p80, CD121 antigen-like family member A, Interleukin-1 receptor type 1
Anti-IL1R1 Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting IL1R1. Anti-IL1R1 Monoclonal Antibody-APC can be used in ELISA, FACS.
Anti-IL1R1 Monoclonal Antibody-APC
Anti-IL1R1 Monoclonal Antibody-APC
产品编号 TMAZ-0067A 别名 Interleukin-1 receptor alpha, Interleukin-1 receptor type I, p80, CD121 antigen-like family member A, Interleukin-1 receptor type 1
Anti-IL1R1 Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting IL1R1. Anti-IL1R1 Monoclonal Antibody-APC can be used in ELISA, FACS.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μg | 询价 | 7日内发货 | |
| 100 μg | 询价 | 7日内发货 |
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| 产品描述 | Anti-IL1R1 Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting IL1R1. Anti-IL1R1 Monoclonal Antibody-APC can be used in ELISA, FACS. |
| 别名 | Interleukin-1 receptor alpha, Interleukin-1 receptor type I, p80, CD121 antigen-like family member A, Interleukin-1 receptor type 1 |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of IL1R1 overexpressed 483F cells with TMAZ-0067A, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| 应用 | ELISA, FACS |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Single-pass membrane protein |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IL1R1 protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 研究背景 | Receptor for IL1A, IL1B and IL1RN (PubMed: 2950091, PubMed: 37315560). After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (PubMed: 10653850) |
| 偶联 | APC |
| 其他可选修饰符 | Biotin/PE/AF488/AF555/AF647 |
| 可提供抗体种类 | 1 |
| 免疫原 | IL1R1 |
| 抗原种属 | Human |
| 基因ID | 3554 |
| Uniprot ID | |
| 研究领域 | Immunology Research |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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