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Anti-IL7 Monoclonal Antibody-Biotin
产品编号 TMAZ-0206B
Anti-IL7 Monoclonal Antibody-Biotin is a Biotin-conjugated humanized rabbit antibody targeting IL7. Anti-IL7 Monoclonal Antibody-Biotin can be used in ELISA, FACS.
Anti-IL7 Monoclonal Antibody-Biotin
Anti-IL7 Monoclonal Antibody-Biotin
产品编号 TMAZ-0206B
Anti-IL7 Monoclonal Antibody-Biotin is a Biotin-conjugated humanized rabbit antibody targeting IL7. Anti-IL7 Monoclonal Antibody-Biotin can be used in ELISA, FACS.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μg | 询价 | 7日内发货 | |
| 100 μg | 询价 | 7日内发货 |
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产品介绍
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偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-IL7 Monoclonal Antibody-Biotin is a Biotin-conjugated humanized rabbit antibody targeting IL7. Anti-IL7 Monoclonal Antibody-Biotin can be used in ELISA, FACS. |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of IL7 overexpressed 490F cells with TMAZ-0206B, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| 应用 | ELISA, FACS |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IL7 protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| 纯度 | Greater than 95%, as determined by SDS-PAGE. |
| 研究背景 | Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis (PubMed: 25870237, PubMed: 7527823). Mechanistically, exerts its biological effects through a receptor composed of IL7RA subunit and the cytokine receptor common subunit gamma/CSF2RG (PubMed: 8128231). Binding to the receptor leads to activation of various kinases including JAK1 or JAK3 depending on the cell type and subsequently propagation of signals through activation of several downstream signaling pathways including the PI3K/Akt/mTOR or the JAK-STAT5 (PubMed: 18523275, PubMed: 20974963) |
| 偶联 | Biotin |
| 其他可选修饰符 | APC/PE/AF488/AF55/AF647 |
| 可提供抗体种类 | 1 |
| 免疫原 | IL7 |
| 抗原种属 | Human |
| 基因ID | 3574 |
| Uniprot ID | |
| 研究领域 | Drug Target |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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