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Anti-TIMP1 Monoclonal Antibody-AF488
产品编号 TMAZ-0042A4
别名 Fibroblast collagenase inhibitor, Erythroid-potentiating activity, Tissue inhibitor of metalloproteinases 1, Metalloproteinase inhibitor 1
Anti-TIMP1 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting TIMP1. Anti-TIMP1 Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
Anti-TIMP1 Monoclonal Antibody-AF488
Anti-TIMP1 Monoclonal Antibody-AF488
产品编号 TMAZ-0042A4 别名 Fibroblast collagenase inhibitor, Erythroid-potentiating activity, Tissue inhibitor of metalloproteinases 1, Metalloproteinase inhibitor 1
Anti-TIMP1 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting TIMP1. Anti-TIMP1 Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μg | 询价 | 7日内发货 | |
| 100 μg | 询价 | 7日内发货 |
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产品介绍
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偶联与修饰
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| 产品描述 | Anti-TIMP1 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting TIMP1. Anti-TIMP1 Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF. |
| 别名 | Fibroblast collagenase inhibitor, Erythroid-potentiating activity, Tissue inhibitor of metalloproteinases 1, Metalloproteinase inhibitor 1 |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of TIMP1 overexpressed 303F cells with TMAZ-0042A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| 应用 | ELISA, FACS, IF |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of TIMP1 protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 研究背景 | Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors |
| 偶联 | AF488 |
| 其他可选修饰符 | Biotin/APC/PE/AF555/AF647 |
| 可提供抗体种类 | 3 |
| 免疫原 | TIMP1 |
| 抗原种属 | Human |
| 基因ID | 7076 |
| Uniprot ID | |
| 研究领域 | Immunology Research |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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