IL-10R alpha/IL-10RA Protein, Macaca mulatta, Recombinant (His)

产品编号 TMPJ-01424

Interleukin-10 Receptor alpha (IL-10 R alpha), also known as IL-10 R1, is transmembrane glycoprotein member of the class II cytokine receptor family. Interleukin-10 (IL10) is a key anti-inflammatory cytokine that is produced predominantly by leukocytes including T cells, B cells, monocytes, macrophages, and dendritic cells (DCs), as well as by some epithelial cells. The receptor for IL10 is a heterotetramer complex comprising two IL10Ra (also referred to as IL10R1) molecules and two IL10Rb (also referred to as IL10R2) molecules.IL10Ra is expressed on most hematopoietic cells at a basal level but is upregulated by various cells upon activation, suggesting its importance in inhibitory pathways.

IL-10R alpha/IL-10RA Protein, Macaca mulatta, Recombinant (His)

产品编号 TMPJ-01424

规格	价格	库存
10 μg	¥ 950	5日内发货
50 μg	¥ 2,860	5日内发货
500 μg	¥ 16,800	5日内发货
1 mg	¥ 25,200	5日内发货

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生物活性

生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	Interleukin-10 Receptor alpha (IL-10 R alpha), also known as IL-10 R1, is transmembrane glycoprotein member of the class II cytokine receptor family. Interleukin-10 (IL10) is a key anti-inflammatory cytokine that is produced predominantly by leukocytes including T cells, B cells, monocytes, macrophages, and dendritic cells (DCs), as well as by some epithelial cells. The receptor for IL10 is a heterotetramer complex comprising two IL10Ra (also referred to as IL10R1) molecules and two IL10Rb (also referred to as IL10R2) molecules.IL10Ra is expressed on most hematopoietic cells at a basal level but is upregulated by various cells upon activation, suggesting its importance in inhibitory pathways.
种属	Macaca Mulatta
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	XP_028689862.1
别名	IL-10RA,Interleukin-10 receptor subunit 1,IL-10R subunit 1,IL-10R subunit alpha,Interleukin-10 receptor subunit α,IL-10 receptor subunit α,IL-10 receptor subunit alpha,IL-10R1,IL10RA,IL-10R subunit α,CDw210a,CD210,Interleukin-10 receptor subunit alpha
氨基酸序列	His22-Asn235
蛋白构建	His22-Asn235
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	35-55 KDa (reducing condition)
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Interleukin-10 Receptor alpha (IL-10 R alpha), also known as IL-10 R1, is transmembrane glycoprotein member of the class II cytokine receptor family. Interleukin-10 (IL10) is a key anti-inflammatory cytokine that is produced predominantly by leukocytes including T cells, B cells, monocytes, macrophages, and dendritic cells (DCs), as well as by some epithelial cells. The receptor for IL10 is a heterotetramer complex comprising two IL10Ra (also referred to as IL10R1) molecules and two IL10Rb (also referred to as IL10R2) molecules.IL10Ra is expressed on most hematopoietic cells at a basal level but is upregulated by various cells upon activation, suggesting its importance in inhibitory pathways.

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关键词

CD 210 CD-210