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MMP-12 Protein, Mouse, Recombinant (His)

产品编号 TMPJ-00942

Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

MMP-12 Protein, Mouse, Recombinant (His)

MMP-12 Protein, Mouse, Recombinant (His)

产品编号 TMPJ-00942
Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
规格价格库存数量
10 μg¥ 1,1705日内发货
50 μg¥ 3,4705日内发货
500 μg¥ 12,1005日内发货
1 mg¥ 18,9005日内发货
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生物活性

生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述
Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
种属
Mouse
表达系统
HEK293 Cells
标签C-6xHis
蛋白编号P34960
别名
Mme,Mmp12,MMP-12,Mmel,Matrix metalloproteinase-12,Macrophage metalloelastase
氨基酸序列
Ala29-Cys473
蛋白构建
Ala29-Cys473. The proenzyme needs to be activated by APMA for an activated form.
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
MMP-12 Protein, Mouse, Recombinant (His)
分子量64 KDa (reducing condition)
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液Supplied as a 0.2 μm filtered solution of 20 mM PB, 500 mM NaCl, 0.01%Tween 80, 1 mM EDTA, 50% Glycerol, pH6.0.
存储
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景
Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

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