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IFN-alpha 2b/IFNA2 Protein, Human, Recombinant
产品编号 TMPJ-00746
At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences by only one or two positions. Naturally occurring variants also include proteins that are truncated by 10 amino acids at the carboxyl-terminal end.
IFN-alpha 2b/IFNA2 Protein, Human, Recombinant
产品编号 TMPJ-00746
At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences by only one or two positions. Naturally occurring variants also include proteins that are truncated by 10 amino acids at the carboxyl-terminal end.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 10 μg | ¥ 380¥ 220.4 | 现货 | |
| 20 μg | ¥ 590 | 5日内发货 | |
| 50 μg | ¥ 1,090 | 5日内发货 | |
| 100 μg | ¥ 1,470 | 5日内发货 |
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生物活性
| 生物活性 | 1. Loaded Human IFNAR2-Fc on Protein A Biosensor, can bind Human IFN alpha2b with an affinity constant of 2.98 nM as determined in BLI assay. (Regularly tested)
2. Measured in antiviral assay using A549 human lung cancer cells infected with vesicular stomatitisvirus (VSV) The ED50 for this effect is 5 ng/mL. (Regularly tested)   |
| 产品描述 | At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences by only one or two positions. Naturally occurring variants also include proteins that are truncated by 10 amino acids at the carboxyl-terminal end. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | Tag Free |
| 蛋白编号 | P01563 |
| 别名 | 干扰素,IFNA2,Interferon α-2,Interferon α-A,Interferon Alpha-2,IFN-α-2,LeIF A,Interferon Alpha-A,IFN-Alpha-2,IFN α2b |
| 氨基酸序列 | Cys24-Glu188 |
| 蛋白构建 | Cys24-Glu188 |
| 蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.   |
| 分子量 | 17 KDa (reducing condition) |
| 内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.2. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 研究背景 | At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences by only one or two positions. Naturally occurring variants also include proteins that are truncated by 10 amino acids at the carboxyl-terminal end. |
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