amyloid β peptide

β-Amyloid (1-42), (rat mouse) (TFA) 是由 42 个氨基酸组成的多肽片段，可用于研究阿尔茨海默症。

β-Amyloid (25-35) (Aβ25-35) 是一种阿尔茨海默氏淀粉样蛋白β肽的Aβ(25-35) 片段，在培养细胞中显示出神经毒性作用。

β-Amyloid (1-42), acetate (human) 是由 42 个氨基酸组成的肽，是 β-Amyloid 的一部分，常用于阿尔茨海默病造模。

β-amyloid 1-11 acetate(190436-05-6 free base) 是 Amyloid-β 肽的片段，可用于神经系统疾病的研究。

β-Amyloid 15-21 acetate (Beta-Amyloid(15-21) acetate) 是 Amyloid-β 肽的片段，可用于神经系统疾病的研究。该片段参与β折叠形成。

Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) 是 Amyloid-β 肽的片段，可能用于神经系统疾病的研究。Amyloid β 蛋白片段含有 α-分泌酶加工位点（Lys16-Leu17 键）。它还包含负责与小胶质细胞结合的 HHQK 结构域（残基 13-16）。

GSNKGAIIGLM(131602-53-4(free base)) (Amyloid beta-peptide(25-35)) 是阿尔茨海默病淀粉样蛋白 β-肽的片段 Aβ(25-35)。

Colivelin 是一种神经保护肽和 STAT3 的激活剂，是一种合成的杂合肽，可增强 humanin (HN) 的神经保护作用。它通过激活 STAT3 在体外抑制神经元死亡，具有潜力用于阿尔茨海默病和缺血性脑损伤的相关研究。

β-Amyloid (31-35) (β-Amyloid 31-35) 是一种天然 Amyloid-β 肽的最短序列，具有神经毒性。

Amyloid β Peptide (42-1)(human) acetate 是淀粉样蛋白 β 肽 (1-42) 的无活性形式。Amyloid β Peptide (42-1)(human) acetate 是由 42 个氨基酸组成的肽，其在阿尔茨海默病的发病机制中起关键作用。

β-Amyloid peptide(16-20)，即 Amyloid-β(Abeta) 的氨基酸序列(KLVFF)部分，有效抑制 Abeta 原纤维形成，通过在 N 和 C 末端添加 RG-/-GR-NH2 残基增强其溶解性。

Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red and are organized in a cross-β arrangement of β-strands similar to Aβ (1-40) and Aβ (1-42) fibrils. Aggregated Aβ (25-35) decreases the viability of rat adrenal PC12 cells. It also decreases the viability of primary rat cortical neurons at concentrations ranging from 1 nM to 30 μM. In vivo, intracerebral injection of Aβ (25-35) (20 nmol) in rats induces lesions of neuronal and tissue loss. Aggregated Aβ (25-35) administered intracerebroventricularly to rats induces learning and memory impairments in the Y-maze, novel object recognition, and contextual fear conditioning tests.

Amyloid-Forming peptide GNNQQNY是由酵母蛋白Sup35的N-末端朊病毒决定结构域中得来的七肽段，具有生物活性，并能形成淀粉样纤维。它的详细原子低聚结构之研究，使其成为揭示早期聚集阶段的理想模型。GNNQQNY二聚体以三种稳定构形存在：寄存器内并排、寄存器外并排和反向并排。对准的平行二聚体其β-pleated sheet结构中肽链间氢键较少，强调了疏水作用的重要性，相较于反向并排结构有更高的构象熵。

Amyloid precursor c-terminal peptide has the amino acid sequence Gly-Tyr-Glu-Asn-Pro-Thr-Tyr-Lys-Phe-Phe-Glu-Gln-Met-Gln-Asn. APP is best known as the precursor molecule whose proteolysis generates beta-amyloid (Aβ), a 37 to 49 amino acid peptide whose am

Biotin-β-Amyloid (1-42), human TFA（Biotin-Amyloid β-Peptide (1-42) (human) TFA）是一种标记有生物素的β-Amyloid (1-42)肽，由42个氨基酸构成，对阿尔茨海默病的发病机理有重要作用。

β-Amyloid (1-42), human 是一种由 42 个氨基酸组成的肽，在阿尔茨海默病的发病机制中起关键作用。

Rat form of the beta-Amyloid (1-40) peptide

Amyloid (1-42), rat is a polypeptide composed of 42 amino acids. It is toxic to hippocampal slices and can be used in the study of alzheimer's disease.

β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42) which plays a key role in the pathogenesis of Alzheimer disease.

(Gln22,Asn23)-Amyloid β-Protein (1-40) 为特定多肽，主要应用于研究脑淀粉样血管病的相关突变。

[Arg6]-β-Amyloid (1-40), England mutation 是具有生物活性的肽，与多种家族性常染色体显性阿尔茨海默病相关。特别地，这种英国突变，即位于第6位的His被Arg所替换，已报告可提高寡聚体形成动力学，加速初级纤维的种子化过程。此类寡聚体对神经元培养细胞展现出较高毒性。

Cys-Gly-Lys-Arg-Amyloid β-Protein (1-42) 为淀粉样β蛋白（Aβ）的一段肽片段, 主要应用于阿尔茨海默病研究中。

(Nle35)-Amyloid β-Protein (1-42) ammonium 是一种肽。

β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid. It exhibits the ability to bind to metal ions, indicating its involvement in metal-binding processes. β-Amyloid, a peptide, is responsible for the formation of amyloid plaques in the brains of individuals affected by Alzheimer's disease (AD).

β-Amyloid (29-40), a fragment of the Amyloid-β peptide, possesses physical and chemical properties similar to those of viral protein fusion peptides. The C-terminal fragments (29-40 42) of Alzheimer's beta amyloid peptide can induce the fusion of liposomes.

β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells. Beta amyloid (22-35) is a synthetic truncated fragment of beta-amyloid peptide.

Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-secretase processing site (Lys16-Leu17 bond). It also contains the HHQK domain (residues 13-16) re

β-Amyloid (1-16) rat 是β-淀粉样肽 (Abeta) 金属结合域的片段，含有三个与人类相异的氨基酸替代，因此在大鼠和小鼠中降低了 AD 样神经退行性变的易感性。

Exendin (5-39) is a powerful antagonist of the glucagon-like peptide 1 (GLP-1) receptor with the ability to ameliorate memory impairment in rats treated with β-amyloid protein.

Acetly-β Amyloid (15-20), Amide 为多肽片段，具有抑制 Aβ (1–40) 肽β-折叠形成并稳定其结构的功能，适用于阿尔茨海默病的相关研究。

[Arg6]-β-Amyloid (1-42), england mutation 是具有生物活性的肽类化合物。β-Amyloid (1-42)中的英国 (H6R) 突变被认为与Alzheimer病的常染色体显性遗传形式有关，此突变影响了位点H6的相互作用。

(Pyr11)-Amyloid β-Protein (11-40) (A beta 11pE-40) 作为一种肽， 主要应用于阿尔茨海默病相关研究。

(Lys22)-Amyloid β-Protein (1-42) 是 WT Amyloid β-Protein (1-42) 肽的突变。

β-Amyloid (42-1), human TFA 为淀粉样蛋白β肽(1-42)的无活性形式，包含42个氨基酸，对阿尔茨海默病发病机制扮演关键角色。

(Gly22)-Amyloid β-Protein (1-42) 为淀粉样蛋白β-蛋白(Aβ)的一种肽段，主要在阿尔茨海默病患者的血管和脑组织中形成淀粉样沉积。Aβ中Glu22至Gly22的突变显著促进了该蛋白的聚集。

β-Amyloid (1-40), FAM-labeled is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λ ex = 492 nm and λ em = 518 nm).

Beta-Amyloid(1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. This peptide is amino acids 1 to 14 fragment of Beta-Amyloid peptide.

β-Amyloid (1-42), rat TFA is a 42-aa peptide, shows the effects of cytotoxicity on acute hippocampal slices, and has been used in studies of alzheimer's disease.

β-Amyloid (1-40), FAM-labeled TFA 是一个 FAM 荧光标记的 β-Amyloid (1-40) 肽 (λex=?492?nm and λem=?518?nm)。

(Met(O2)35)-Amyloid β-Protein (1-42) 是一种多肽。

β-Amyloid (1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. β-Amyloid (1-14),mouse,rat is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein (APP), by β- and γ-secretases. β-Amyloid (1-14),mouse,rat accumulation in the brain is proposed to be an early toxic event in the pathogenesis of Alzheimer’s disease, which is the most common form of dementia associated with plaques and tangles in the brain[1]. [1]. Chen GF, et al. Amyloid beta: structure, biology and structure-based therapeutic development. Acta Pharmacol Sin. 2017 Sep;38(9):1205-1235.

β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide. Notably, it serves as the primary constituent of amyloid plaques associated with Alzheimer's disease.

β-Amyloid (33-40) is a peptide consisting of amino acid of 33 to 40 of beta amyloid protein.

β-Amyloid (35-42) is a peptide consisting of amino acid of 35 to 42 of beta amyloid protein.

β-amyloid (15-21) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease. This fragment is involved in beta sheet formation.

β-Amyloid (11-22) is a peptide fragment of β-Amyloid. Beta-amyloid peptide (Abeta), the primary component of amyloid plaques in the brains of Alzheimer’s patients, is believed to be the cause of Alzheimer’s Disease (AD), the most common neurodegenerative disorder.

Amyloid β-Protein (3-42) 为Pyr肽前体, 其焦谷氨酸修饰的形式 Aβ (pEAβ) (3-42) 构成阿尔茨海默病淀粉样斑块的关键。pEAβ (3-42) 能促进 Aβ(1-42) 聚集，并且 Aβ(1-42) 显著延缓pEAβ(3-42) 的初级及次级成核过程。

F(N-Me)GA(N-Me)IL 是一种双N-甲基化衍生的生物活性肽，缺乏β-折叠结构且不具备淀粉样蛋白形成性及细胞毒性。与天然序列相互作用时，该衍生物能有效抑制淀粉样蛋白的形成。