assemblies

Arimoclomol (BRX-220 free base) 是热休克蛋白 (HSP) 的共诱导剂，可用于治疗肌萎缩侧索硬化症的研究。

Arimoclomol maleate (BRX-220) 是一种热休克蛋白 (HSP) 的共诱导剂。它通过增强 Hsp 表达来保护运动神经元，进而通过蛋白酶体-泛素系统直接影响蛋白质聚集和错误折叠装配体的清除

Arimoclomol citrate (BRX-220 citrate) is a heat shock protein (HSP) co-inducer that acts by enhancing Hsp expression and directly impacting protein aggregation, clearance of misfolded assemblies, and the proteasome-ubiquitin system. This compound is known for its ability to protect motor neurons.

Biotinyl hexylamine is a synthetic intermediate.1,2It has been used in the synthesis of avidin nucleic acid nano assemblies (ANANAS) and chemotherapeutic conjugates for the diagnosis of, and drug delivery to, tumors. 1.Sabatino, G., Chinol, M., Paganelli, G., et al.A new biotin derivative-DOTA conjugate as a candidate for pretargeted diagnosis and therapy of tumorsJ. Med. Chem.46(14)3170-3173(2003) 2.Bigini, P., Previdi, S., Casarin, E., et al.In vivo fate of avidin-nucleic acid nanoassemblies as multifunctional diagnostic toolsACS Nano8(1)175-187(2014)