bam 22p

BAM (8-22) acetate 是脑啡肽原 A 的蛋白水解产物。BAM (8-22) acetate 可激活 Mas 相关的 G 蛋白偶联受体 (Mrgprs)、MrgprC11 和 hMrgprX1，并以 Mrgpr 依赖性方式诱导小鼠抓挠。

Bovine adrenal medulla docosapeptide (BAM-22P) is a potent opioid agonist, derived from the proenkephalin A gene, which is present in the adrenal medulla.

BAM 22P acetate 是一种有效的阿片类药物激动剂。

Endogenous peptide fragment that is a potent agonist for MRGPRX1 (EC50 values are 8 - 150 nM); first isolated from bovine adrenal medulla. Unlike BAM 22P , does not contain the met-enkephalin motif therefore displays no affinity for opioid receptors.

BAM(8-22) TFA 作为前脑啡肽 A 的蛋白水解切割产物，有效激活 Mas 相关 G 蛋白偶联受体（Mrgprs）、MrgprC11 及 hMrgprX1，并能在小鼠中通过 Mrgpr 依赖机制诱发抓挠行为。