enterobacteriaceae

Cefmenoxime hydrochloride (Cefmenoxime hemihydrochloride) 是一种头孢类抗生素，可通过静脉内或肌肉内给药。 它对大多数常见的革兰氏阳性和革兰氏阴性微生物有活性，是一种肠杆菌科抑制剂，并且对 β-内酰胺酶的水解具有高度抗性。

WCK-4234 sodium (WCK 4234) 是一种 β-内酰胺酶抑制剂，可用于针对 MDR 感染的研究。 WCK-4234 sodium 抑制 A、C 和 D 类 β-内酰胺酶和 OXA 碳青霉烯酶。

Relebactam (MK-7655) 是一种有广谱抗β内酰胺酶活性的二氮杂双环辛烷抑制剂。

Glycosyltransferase-IN-1 是一种糖基转移酶 (glycosyltransferase) 抑制剂，具有抑菌活性，抑制 MSSA、MRSA 、枯草杆菌和肠杆菌。

Plazomicin is a next-generation aminoglycoside that has been designed as an antibiotic to avoid resistance through aminoglycoside-modifying enzymes. Plazomicin shows high activity against the Enterobacteriaceae.

SA09-Cu是一种NDM-1的非竞争性抑制剂，具有9.6 nM的IC50。该化合物通过作用于氧化酶的Zn(II)-硫醇盐位点，能将NDM-1转化为无活性形态，从而抵御细菌细胞内的硫醇还原作用。SA09-Cu对于多种产生NDM-1的肠杆菌科碳青霉烯耐药菌株（CRE）表现出明显的抑制作用，有效恢复了美罗培南的活性，并有助于减缓碳青霉烯耐药性的进展。

NOSO-95C is an antibacterial compound that bind to the bacterial ribosome and kill bacteria through inhibition of the translation. NOSO-95C showed promising in vitro and in vivo efficacy against Enterobacteriaceae.

NOSO-502为一种对肠杆菌科表现出抑制效果的细菌翻译(bacterialtranslation)抑制剂，具备良好的安全性及抗菌特性。

Cefmenoxime sodium is the ssalt form of Cefmenoxime (free base), a cephalosporin antibiotic administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganisms. It is a potent inhibitor of Enterobacteriaceae, and is resistant to beta-lactamase-initiated hydrolysis. The drug has a high success rate against many types of infection.

Cefteram (T-2525)为Cefteram pivoxil的游离酸形式，属于具有口服活性的头孢菌素酯类抗生素。该化合物对肠道致病性肠杆菌科与弧菌科细菌表现出有效的抗菌作用。

Cefquinome是一种头孢烯类抗生素，具有抑制多种肠杆菌科细菌的效能。

ANT431 is a novel metallo-β-lactamase inhibitor for the treatment of carbapenem-resistant enterobacteriaceae infections

LYS228 is a potent antibiotics against Carbapenem-Resistant Enterobacteriaceae (MIC90 = 2 uM/mL). LYS228 is potent in the presence of all classes of beta-lactamases.

BMS 180680 is a novel catechol-containing monolactam antibacterial active agent, which is the most effective compound against many species of Enterobacteriaceae.

CP 99433 is a new C-7 diazabicyclofluoroquinolone with a broad spectrum of activity that includes Enterobacteriaceae, Gram-positive cocci, and nonenteric Gram-negative bacilli.

Isepamicin (Sch 21420) is a potent aminoglycoside antibacterial compound with enhanced efficacy against strains harboring type I 6'-acetyltransferase. Its antibacterial spectrum encompasses Enterobacteriaceae and staphylococci, while exhibiting resistance against anaerobes, Neisseriaceae, and streptococci. Moreover, Isepamicin displays a robust concentration-dependent bactericidal effect, a prolonged post-antibiotic effect lasting several hours, and is capable of inducing adaptive resistance.

Cefmenoxime is a cephalosporin antibiotic administered intravenously or intramuscularly. It is an effective inhibitor of Enterobacteriaceae and is resistant to beta-lactamase-initiated hydrolysis. It is active against most common gram-positive and gram-ne

Cefquinome sulfate 是一种半合成的头孢烯广谱抗生素，具有抗菌活性。