hdhodh in 7

hDHODH-IN-7 (DHODH-IN-9) 是一种含嗪的类似物，是一种人二氢乳清酸酯脱氢酶抑制剂。hDHODH-IN-7 具有抗病毒作用，pMIC50 为 7.4。

hDHODH-IN-5 是人源二氢乳清酸脱氢酶的抑制剂 (hDHODH, IC50 = 0.91 μM)。

hDHODH-IN-9 (Compound 3k) is a highly potent inhibitor of hDHODH, exhibiting an IC50 of 0.34 μM. It displays significant cytotoxic activity against MCF-7 and A375 cells, while maintaining good selectivity. With its characteristics, hDHODH-IN-9 holds promise for cancer disease research [1].