mpep

MPEP 是一种选择性 mGlu5 受体拮抗剂，IC50 为 36 nM，有抗焦虑和抗抑郁活性。

MPEP Hydrochloride 是一种有效且高度特异性的非竞争性拮抗剂，作用于 mGlu5 受体亚型，IC50为 36 nM，有抗焦虑和抗抑郁活性。

VU 0285683 是 mGluR5 的特异性负变构调节剂，对 MPEP 结合位点具有高亲和力。 VU 0285683 表现出抗焦虑样活性。

是一种化学合成中的砌块

5-MPEP is a neutral allosteric site ligand of the metabotropic glutamate receptor subtype 5 (mGlu5), blocking the effects of both the allosteric antagonist MPEP and potentiator CDPPB.

M-5MPEP is a mGlu5 antagonist.

MMPEP is both a selective non-competitive mGlu5 receptor antagonist with IC50 value of 36 nM and a mGlu4 receptor positive allosteric modulator.

Incadronate, also known as Cimadronate and YM-175, is a bone resorption inhibitor. Incadronate disodium inhibits macrophage migration to site of inflammation in vivo and proliferation and causes apoptosis in cancer cells in vitro. Incadronate disodium is a bone density conservation, antitumor and anti-inflammatory agent.